Plants and other natural sources can provide a huge range of complex and structurally diverse compounds. Microbial and plant products occupy the major part of the antimicrobial compounds discovered until now. They are derived from prokaryotic bacteria, eukaryotic microorganisms, plants and various animal organisms. Natural products are still one of the major sources of new drug molecules today. įor this reason, discovery of new antibiotics is an exclusively important objective. Currently, its impact is considerable with treatment failures associated with multidrug-resistant bacteria and it has become a global concern to public health. In this review, we focused on the use of antimicrobial testing methods for the in vitro investigation of extracts and pure drugs as potential antimicrobial agents.Īfter the revolution in the “golden era”, when almost all groups of important antibiotics (tetracyclines, cephalosporins, aminoglycosides and macrolides) were discovered and the main problems of chemotherapy were solved in the 1960s, the history repeats itself nowadays and these exciting compounds are in danger of losing their efficacy because of the increase in microbial resistance. Antimicrobial susceptibility testing can be used for drug discovery, epidemiology and prediction of therapeutic outcome.
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Or ogres, I want to wipe out the Feralas ogres! More ogres to kill! I never really liked monkeys so wiping them out doesn't seem like such a big deal. Shandris kicked ass though, one of the two major things the night elves got, Shandris kicking ass and gathering an army and we wiping out a troll tribe. It would also probably be a better military stronghold because a large percentage of the Darnassian army is stationed there.YEESSSSSS PLEASE! That would be amazing, honestly! Make it happen Blizzard, that would really wipe some of the disapointment from night elves in Cataclysm. You could also reintroduce Maiev since her character was massively changed in the WoW books. This could also be a big chance to give Shandris Feathermoon some good lore/story-time, since the more militaristic Night Elven characters rarely show their strength. It's definitely big enough to be a strong Alliance base, and it still gives Alliance some position in southern Kalimdor. 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